ingredientVemurafenib 250 mg
substitutesVemurafenib 250 mg
Shipping classRoom Temperature
Medicine Overview by Anukar Pharmacy
( Zelboraf 240mg 56s Tablets )
TreatmentVemurafenib is used to treat a type of skin cancer (melanoma) that has spread or cannot be removed by surgery. It is also used to treat a rare type of blood cell cancer called Erdheim-Chester disease. These cancer cells have a certain type of abnormal ??BRAF?? gene. Vemurafenib works by slowing the growth of certain cancer cells. It belongs to a class of drugs known as kinase inhibitors.
Side Effectsjoint pain, tiredness, nausea, hair loss, rash or itching, skin growths (skin tags), blurred vision, increased sensitivity of your eyes to light, hair loss, thickening skin, rough scaly patches on skin, dry skin, skin redness, muscle pain, pain in extremities, back pain, fatigue, swelling of extremities, fever, weakness, diarrhea, vomiting, constipation, headache, changes in taste, decreased appetite, cough, and sunburn
Method of UseTake this medication by mouth with or without food as directed by your doctor, usually twice daily about 12 hours apart. Swallow whole with a glass of water. Do not crush or chew this medication. If you vomit after taking your dose, do not take an extra dose of this medication. Take the next dose of the medication at the regularly scheduled time.
How WorksVemurafenib belongs to a group of cancer fighting medications called antineoplastics, and more specifically to a group of medications called protein kinase inhibitors. Vemurafenib works by recognizing and attaching to certain types of cancer cells. This may slow down or stop cancers from growing and dividing.
More Info by Anukar Pharmacy
( Zelboraf 240mg 56s Tablets )
Suggestions
- Before taking vemurafenib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
- Before using this medication, tell your doctor or pharmacist your medical history, especially of: radiation therapy.
- Vemurafenib may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
- The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using vemurafenib, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
- Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/??water pills??) or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using vemurafenib safely.
- This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.
- Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
- Older adults may be more sensitive to the side effects of this drug, especially skin changes, nausea, decreased appetite, swelling of ankles/feet/hands, and QT prolongation (see above)
Warning by Anukar Pharmacy
( Zelboraf 240mg 56s Tablets )
Special precautions for ( Zelboraf 240mg 56s Tablets ) Heads up
| aspect | highlight | details |
|---|---|---|
Alcohol
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There is no significant data. | |
Pregnancy
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caution | Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using vemurafenib. Vemurafenib may harm an unborn baby. |
Lactation
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It is unknown if this medication passes into breast milk. Because of possible risk to the infant, breast-feeding while using this medication and for 2 weeks after stopping treatment is not recommended. Consult your doctor before breast-feeding. | |
Driving
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Vemurafenib can cause dizziness, so do not drive. | |
Kidney
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caution | Check with your doctor as soon as possible if any of the following side effects occur signs of kidney failure (e.g., decreased urine production, swelling in the ankles or feet, fatigue, abdominal pain) |
Liver
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caution | Stop using vemurafenib and call your doctor at once if you haveliver problems?Cstomach pain (upper right side), nausea, vomiting, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). |
Suggestion by Anukar Pharmacy on missing a dose
( Zelboraf 240mg 56s Tablets )
If you miss a dose and it is more than 4 hours before your next dose, take it as soon as possible and continue with your regular schedule. If it is less than 4 hours before your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Disclaimer
The information of Anukar Pharmacy is for reference purpose only, and Anukar Pharmacy or Anukar Pharmacy or Anukar Pharmacy is not intended to be a replacement of professional medical advice, diagnosis, or treatment. Anukar Pharmacy suggest to ask the advice of a physician or any qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of anything you have learned from Anukar Pharmacy.
| 药名 | 威罗菲尼, 维莫非尼 |
| 厂家 | 瑞士罗氏 |
| 成分 | ZELBORAF?是一种激酶抑制剂。 |
| 说明 |
威罗菲尼
维莫非尼(Vemurafenib)，以佐博伏Zelboraf品牌名销售，是由Plexxikon（现为Daiichi-Sankyo的一部分）和Genentech开发的用于治疗晚期黑素瘤的B-Raf?酶抑制剂。Vemurafenib用于治疗已经扩散到身体其他部位或无法通过手术切除的黑色素瘤（皮肤癌）。Vemurafenib也可用于治疗Erdheim-Chester病（一种罕见的血液癌）。
治疗作用：适用于有不可切除或转移黑色素瘤有用FDA-批准的检验检测BRAFV600E突变患者的治疗。
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